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Mixing human + animal DNA and the future of gene editing | Big Think

Mixing human+ animal DNA and the future of gene editing
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As information materials that makes all living things what/ who “we ii”, DNA is the key to understanding and changing the world countries. British geneticist Bryan Sykes and Francis Collins, head of the Human Genome Project, please explain how, through gene revising, scientists can better treat afflictions, eradicate sickness, and change personalized medicine.

But existing and developing gene editing technologies are not without quarrels. A major point of debate deals with the idea that gene editing is overstepping natural and ethical bounds. Precisely as they can, does that mean that scientists should edit DNA?

Harvard prof Glenn Cohen initiates another subcategory of gene experimentations: desegregating human and animal DNA. “The question is which are okay, which are not okay, why can we generate some principles, ” Cohen says of human-animal chimeras and contentions concerning improving human rights versus morality.

0:00 Intro
0:41 Bryan Sykes, What We Need to Know About Genes
3:24 Francis Collins, Linking Genes to Disease
8:39 Glenn Cohen, Crossing Human Genes With Animals

BRYAN SYKES: Genetics and DNA does get to the central issue of what reaches us tick. It’s perhaps too determinist be mentioned that your genes establish everything you do. They don’t, but, if you like, it’s like the deck of cards that you’re considered at birth. What you do with that deck, like any card game, depends a lot on your picks, but it is influenced by those cards, those genes that you got when you were born.

What I’ve enjoyed about genetics is looking to see what it tells us about where we’ve come from because those sections of DNA, they came from somewhere. They weren’t just sort of plucked out of the air. They came from ancestors. And it’s a very good way of used to identify about your predecessors , not only who they are, but exactly imagining their lives. You’re made up of DNA from thousands and thousand of ancestors who’ve lived in the past, almost all cases now dead, but they’ve survived, they’ve got through, they’ve progressed their DNA onto their children, and it’s come down to you. It doesn’t matter who you are. You “couldve been” the President. You could be the Prime Minister. You could be the head of a big corporation. You could be a taxi driver. You could be someone who lives on the street. But the same is true of everybody. I can see a meter, long after I’ve gone but when, in fact, everyone will know their relationship to everybody else. It is possible, if anybody wants to do it or can render it, you could actually, I anticipate, proceed the family tree of the entire world by linking up the segments of DNA. So you could find out in what highway everyone was related to everybody else.

No skepticism, most of the funding for the advances in genetics, for example, the terminated sequencing of the human genome, has come from ambition to learn more about health publishes. The engineering for exploring that, which is preparing leaps and bounds, has come through the healthcare benefits. Those are the two main things that people are learning about themselves and who they’re related to, where they’ve come from. And that does, and I know from experience, that does add a lot to people’s sense of identity. It’s not for everybody , not everyone’s so interested in it, but a good deal of beings are and I think that’s a very good thing.

FRANCIS COLLINS: It’s too bad that you can’t actually interpret DNA easily under a microscope and scan across the double-helix and read out of the string of footings that amounts to the information content because it would be easier, I conceive, to explain then how a geneticist leads about tracking down the molecular basis of a disease at the DNA level. Our techniques are indirect. They’re very powerful, they’re very highly accurate, but they’re not as visual as you are able to like. We do have methods though now that allow you to read out with high-pitched accuracy all 3 billion of the letters of the DNA instruction book. Those letters are actually these chemical groundworks. The chemical speech of DNA is a simple one. There’s only four letters in the alphabet. Those cornerstones that we abridge, A, C, G, and T. And we have methods of being able to compare then the DNA sequence of people who have a disease versus people who don’t and look for the critical differences in order to nail down something that might be the campaign. Well, since, nonetheless, we all is different than our DNA sequence by about a half of 1 %, you wouldn’t get very far if you basically…

To read the full record, please visit https :// the-future-of-gene-editing

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